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Francis –
Anabolic Basics For Beginners: The Guide
Anabolic-androgenic steroids (AAS) are synthetic hormones that mimic the effects of the hormone testosterone.
They are often used by bodybuilders and athletes to enhance muscle growth, strength, and performance.
While they can be effective, it’s important to approach their use with caution and a solid understanding of how they work,
both in terms of benefits and potential risks.
**Steroid Cycles 101: Testosterone, PCT, and the KISS Rule**
A steroid cycle refers to the period during which an individual uses AAS,
typically followed by a post-cycle therapy (PCT) phase to restore hormonal balance.
The KISS rule—Keep It Simple, Stupid—is often cited as a
guideline for beginning users: start with one compound, use it at a reasonable
dose, and avoid combining multiple steroids unless
you have experience.
**Introduction to Anabolic-Androgenic Steroids (AAS)**
AAS are man-made hormones that mimic the effects of testosterone.
They bind to androgen receptors in the body, promoting
muscle growth, fat loss, and increased strength.
Common AAS include Testosterone, Dianabol (Metandienone),
Deca-Durabolin (Nandrolone Decanoate), and Trenbolone Acetate.
**Injectable and Oral Steroids**
Steroids can be administered either orally or via injection. Injectable steroids are often preferred for their sustained release of hormones,
while oral steroids like Dianabol and Anavar (Oxandrolone) are convenient but may
have more side effects due to the digestive system’s impact on absorption.
**Oral AAS**
Oral steroids such as Dianabol and Anavar are popular among athletes and bodybuilders.
They work quickly, providing noticeable gains in muscle mass and strength within weeks.
However, they also carry a higher risk of side effects due to their metabolization by the liver.
**Injectable AAS**
Injectable steroids like Testosterone and Deca-Durabolin are favored for their consistent release and lower side effect profiles compared to oral
versions. They can be administered less frequently,
making them more convenient for some users.
**Cycling, Stacking, and Pyramiding Steroids**
Steroid cycling refers to using a compound in a repeated
cycle, typically followed by a PCT to reset the body’s hormonal system.
Stacking involves using multiple compounds at once, while pyramiding
entails increasing doses during the cycle to maximize muscle growth.
**Cycling Steroids**
Steroid cycling involves using a single steroid for one full cycle length, typically ranging from short (2-4 weeks) to long cycles (3-9 months).
The choice of cycle length depends on the user’s goals and experience level.
**Stacking Steroids**
Stacking combines different steroids with complementary effects, such as
Testosterone and Dianabol, to enhance muscle growth and strength.
Advanced users often stack multiple compounds for a synergistic effect, but this comes with
greater risk of side effects.
**Pyramiding Steroids**
Pyramiding involves increasing the dose of a steroid during
the cycle, typically peaking at the midpoint or end
of the cycle. This method is often used to maximize muscle growth but requires
careful planning and monitoring of side effects.
**Cycle Length**
Cycle length varies based on individual goals and experience:
– **Short Cycles (2-4 weeks):** Ideal for achieving quick gains,
often used in combination with PCT.
– **Medium Cycles (6-8 weeks):** Balance between quick results and manageable side effects.
– **Standard Cycles (10-12 weeks):** Common for natural athletes and beginners.
– **Long Cycles (3-9 months):** Typically used by
advanced users or those with specific goals, such as contest preparation.
**Which Steroid Compound to Use?**
The choice of steroid depends on individual needs and preferences:
– **Testosterone (and Its Esters):** The cornerstone of most cycles,
available in various ester forms like Testosterone Propionate or
Enanthate.
– **Dianabol:** A potent oral steroid with rapid effects on muscle mass.
– **Deca-Durabolin:** A milder, longer-acting steroid with excellent
results for muscle growth.
– **Anavar:** A mild oral steroid often used in cutting phases to maintain muscle mass while losing fat.
– **Sustanon 250:** A blend of testosterone esters designed for consistent release over several weeks.
**Beginner Steroid Cycles**
For beginners, starting with simple cycles
is recommended. Common options include:
– **Testosterone-only Cycle**:
– Testosterone Propionate or Enanthate at a low dose (100-300mg/day).
– Followed by a PCT with Clomid or Nolvadex to restore hormonal balance.
– **Testosterone and Dianabol Cycle**:
– Combine Testosterone Propionate with Dianabol at a moderate dose for a balanced approach.
– Ensure adequate PCT after the cycle.
– **Deca-Durabolin and Dianabol Cycle**:
– Use Deca-Durabolin as the base steroid, supplemented with Dianabol for added strength and size.
– Follow a thorough PCT to avoid hormonal imbalances.
**Should I use steroids?**
Deciding whether to use steroids should consider factors like:
– **Age:** Users under 25 may experience permanent
damage to their endocrine system, making steroid use particularly risky.
– **Experience:** Beginners with less than five years of training and poor diet discipline are less likely to see
significant gains.
– **Weight:** Carrying excess body fat can hinder progress, but steroid use is not a substitute for poor diet or lack of exercise.
– **Emotional Issues:** Steroid use can exacerbate mood swings and emotional instability.
**Testosterone in Every Cycle**
Testosterone is the foundation of most steroid cycles.
It’s essential to understand its role in muscle growth, recovery, and overall health.
Regardless of the compound used, a properly designed cycle should include Testosterone or its esters to maintain anabolic activity.
**Your First Cycle**
For first-time users, starting with a simple Testosterone-only cycle
is ideal. Here are two common options:
– **Option #1:** Testosterone Propionate at 100mg/day
for 4 weeks, followed by a PCT.
– **Option #2:** Testosterone Enanthate at 300mg/week for 12 weeks, followed by a PCT
with Clomid and Nolvadex.
**Test Taper Protocol**
Tapering is the practice of reducing doses during the cycle to minimize side effects while maintaining muscle growth.
A common protocol involves starting at a higher dose
and gradually decreasing it over the course of the cycle.
**The 1-vial Testosterone Cycle for Beginners**
Using one vial of Testosterone Enanthate (100mg) per week is an excellent starter cycle for beginners.
This dose is moderate enough to produce noticeable results
without causing severe side effects.
**Testosterone-only Cycle**
– Dose: 300-500mg of Testosterone Propionate daily, divided into two injections (e.g., 150mg
EOD).
– Duration: 4-6 weeks, followed by a PCT with Clomid and Nolvadex.
**Testosterone and Dianabol Cycle**
– Testosterone: 300mg Propionate daily.
– Dianabol: 25-50mg every other day (5-10 days).
– Duration: 6-8 weeks, followed by PCT with
Clomid and Nolvadex.
**Deca-Durabolin and Dianabol Cycle**
– Deca-Durabolin: 50mg weekly.
– Dianabol: 25-50mg every other day (5-10 days).
– Duration: 12 weeks, followed by a PCT with Clomid and Nolvadex.
**Advanced Steroid Cycles**
For more experienced users, advanced protocols like high-dose Testosterone cycles or complex stacking combinations can be employed.
However, these come with increased risk and
require meticulous planning to avoid complications.
**Mistaking Yourself as an Advanced User**
It’s easy for beginners to overcomplicate their steroid use by attempting advanced protocols
before mastering the basics. Always prioritize safety and recovery,
even when pursuing more complex cycles.
**Advanced Steroid Cycle Protocols**
– **High-Dose Testosterone Cycles:** Use doses of 400-800mg/day for
short periods (2-4 weeks) to maximize muscle growth.
– **Test Prop + Trenbolone Acetate:** Combine for a powerful
bulking stack with minimal side effects when properly managed.
– **Long Cycles:** Extend the duration of Testosterone use to
12-16 weeks for longer-lasting gains, but be prepared
for more pronounced PCT requirements.
**What about the doses, you might be asking?**
Doses vary widely based on experience and goals. Bulking
stacks often involve higher doses of compounds like Dianabol and Testosterone, while cutting
stacks focus on milder steroids with minimal side effects.
**Bulking Stacks**
– **Dbol + Tren + Test:** A classic combination for rapid mass gain, using moderate doses of
each compound.
– **Deca Durabolin + Dbol + Test:** Combines long-lasting gains
with rapid results.
– **Sustanon + Tren + Anadrol:** High-dose stack designed for maximum muscle growth.
**Cutting Stacks**
– **Anavar + Winstrol:** A popular cutting combination that preserves muscle while promoting fat loss.
– **Primobolan + Anavar + Deca + Test:** A versatile stack for maintaining muscle and improving conditioning.
– **Test Prop + Tren + Halotestin + Anavar:** A powerful combo for shredded, defined muscle while minimizing fat gain.
**Cycle Diet, Supplements and Training**
– **Training:** Focus on progressive overload, compound movements, and consistency rather
than intensity.
– **Diet:** Maintain a calorie surplus with high protein intake to support muscle
growth.
– **Supplements:** Consider adding BCAAs, creatine, and glutamine for enhanced recovery and performance.
**Post Cycle Therapy (PCT) After Your First
Cycle**
PCT is essential after finishing a steroid cycle to
restore your body’s natural testosterone production and avoid hormonal imbalances.
Common protocols include Clomid or Nolvadex, often taken for 4-6
weeks after the cycle ends.
**Common Side Effects of Steroid Use**
– **Physical:** Acne, hair loss, mood swings, and increased risk of infections.
– **Hormonal:** Testosterone suppression, gynecomastia (breast development), and infertility.
– **Psychological:** Increased aggression, anxiety, and emotional
instability.
**FAQs**
**What are anabolic-androgenic steroids (AAS)?**
They are synthetic hormones with effects similar to testosterone,
often used for muscle growth and performance enhancement.
**What is a half-life?**
Half-life refers to how quickly a substance is metabolized by the body; shorter
half-lives mean compounds need more frequent administration.
**Is it safe to inject steroids? Does it hurt?**
Steroid injections can be safe when done correctly, but
improper administration risks infections and damage to tissues.
Always use sterile equipment.
**At what age should I start using steroids?**
Under 25 is particularly risky due to permanent endocrine system damage; waiting until after 30 is generally advised.
**What should my diet and training be like when I’m on a steroid cycle?**
Maintain a high-protein diet, train hard with adequate rest, and avoid excessive calorie
intake unless bulking.
**What is an ester?**
Esters are chemical compounds that extend the activity of hormones;
in steroids, they determine how long the compound remains
active in the body.
**Should I take anti-estrogen drugs with steroids?**
Yes, to prevent gyno and maintain hormonal health during and after cycles.
**What is gyno?**
Gynecomastia is breast development in males due to elevated estrogen levels.
**Will steroids give me acne or make me bald?**
Yes, they can cause acne and hair loss, especially in men.
**Will steroids affect my sex drive?**
High doses can suppress libido, but this is often reversible with proper PCT.
**How fast do anabolic steroids work?**
Results vary by individual, compound, and dosage; some notice changes within weeks, while others take months.
**What happens when you stop taking steroids?**
Hormonal imbalance and muscle atrophy are possible, which is why PCT
is crucial.
**Final Thoughts**
Steroid use is a serious decision with significant health risks.
Always prioritize natural growth through proper diet, training,
and recovery before considering synthetic aids.
Remember that progress takes time and steroids
carry long-term consequences. Who am I? You are
an individual with unique goals and responsibilities; steroid use should never overshadow these.
Stay safe and make informed decisions for your health and
well-being.
My homepage: anabolic steroid Prescriptions
Betty –
You’re likely to see a fantastic enchancment in the quantity
of weight you can carry when utilizing Anavar.
It has a excessive anabolic ranking, but this doesn’t translate into powerful
anabolic results that can rival those of true bulking steroids (which are nearly
all the time injectables). It’s fun to examine out earlier than and
after photographs of individuals who’ve used Anavar, but this tells us nothing about
any positive aspects in power they’ve experienced on the cycle.
Potential unwanted aspect effects can embrace deepening of the voice,
body hair progress, clitoral enlargements, and menstrual irregularities.
In the Usa and lots of other nations, Anavar is a controlled substance and illegal to possess or
promote without a prescription. In addition to the potential well being
dangers, shopping for Anavar from unregulated sources can even pose a danger of fraud and counterfeiting.
Many sellers of Anavar on the market on-line could promote counterfeit or contaminated merchandise that can be harmful to the user.
In this blog, we are going to discover the
Anavar cycle, the results of Anavar use, its advantages
and dangers, and address some key questions like Anavar UK
purchase, Anavar value, and Anavar outcomes after 2 weeks.
The effects of oxandrolone on the growth hormone and gonadal axes in boys with constitutional delay of growth
and puberty. (2) Schimrigk, Häusler, G., Blümel, P., Plöchl, E., Waldhör, T., & Frisch,
H. We have found that valerian root supplements may be efficient for gentle
insomnia, reducing the time taken to fall asleep and the quality of sleep (36, 37).
In one examine, individuals reached sleep 36% sooner after a single dose of valerian (38).
A strategy to stop overstimulation is to take Anavar doses earlier
in the day. In phrases of food choice, principally clear meals selections should be
consumed, together with unrefined carbohydrates
and unsaturated fats. Healthy meals that are not high in sodium will inhibit water retention, adding to the dry and outlined look that Anavar encourages.
This can present safety issues, so you should only contemplate a provider with a stable status for delivering a
high quality product. Anavar is especially good at getting
rid of fats in additional cussed areas, and for women,
this is usually across the thighs and buttocks. Although total physique weight
may not drop or change much, this is due to muscle gain – fat is still being misplaced.
On a proper food regimen, girls can expect to lose 5-10lbs of fats on an Anavar cycle except they are lean. One of the larger risks of oral steroids is how they can stress the liver,
potentially inflicting liver damage or poisonous hepatitis36.
Clenbuterol burns a major quantity of subcutaneous fat, much like Anavar; thus, combining these two
compounds will end in important fat loss. We find injectable trenbolone poses little danger to
the liver in moderate doses, with it quickly entering the bloodstream instead of passing via the liver.
Nevertheless, methyltrienolone, or oral trenbolone, is severely hepatotoxic and consequently is now not utilized in drugs, with analysis deeming its toxicity unacceptable (31).
A common rip-off we now have been made aware of is sellers labeling merchandise as Anavar, but the uncooked ingredient being Dianabol.
Initially developed to help patients get well from severe weight reduction attributable to surgical procedure, trauma, or continual
sickness, it is now in style amongst athletes and bodybuilders for slicing cycles.
Anavar promotes lean muscle retention, improves muscle
definition, and enhances vascularity with out causing important water
retention. Anavar, scientifically often recognized as Oxandrolone, is among the hottest anabolic
steroids utilized by bodybuilders, athletes, and health lovers worldwide.
Recognized for its gentle but effective nature, Anavar
is very wanted for those seeking to improve strength, promote lean muscle mass,
and accelerate fats loss. Anavar 50 mg is understood for sustaining lean muscle mass during slicing cycles,
permitting users to retain energy whereas losing fat.
It has minimal androgenic effects, reducing the danger of unwanted side
effects like hair loss, zits, or virilization, making it suitable for
both genders. Anavar enhances energy and efficiency without including bulk, ideal for
athletes in weight-specific categories.
With the exception of Hi-Tech Prescribed Drugs, no other complement company has figured
out the way to sort out the arginase problem head-on…
Hi-Tech utilizes ABH and BEC, the novel arginase inhibitors in Anavar®, to flank the
excessive dosage of L-arginine and to take arginase head-on by rendering it useless.
This leaves an abundance of L-arginine uncompromised within the
muscle pool to create a wealth of NO, leading to most muscular vasodilation. Excess water retention makes you look puffy (fatter) than you really are.
Whereas taking Oxanivar™, the extra water flushes out of your system, keeping your pores and skin tight
and lean. A descriptive study of antagonistic occasions from clenbuterol misuse and abuse for weight reduction and bodybuilding.
(17) Malhotra, A., Poon, E., Tse, W. Y., Pringle,
P. J., Hindmarsh, P. C., & Brook, C. G.
For women first treading into the world of AAS, Anavar is type
of all the time the FIRST alternative – and often the only
choice for these desirous to keep away from virilization. You
should not expect important muscle gains – Anavar is not a
bulking steroid, however it can promote some lean positive aspects whereas concurrently
shedding fat. Women can gain within the 10lbs range,
whereas men tend to see smaller features under 10lbs.
When it involves using Anavar for bodybuilding, there are some things
you need to bear in mind in order to get the most out of your cycle.
First, you have to just be sure you are taking the proper dosage on your physique weight and experience degree.
You also need to ensure that you are spacing out your doses evenly all through the day,
and that you’re not taking them too close together.
Additionally, it is very important just remember to are eating a
nutritious diet and getting loads of relaxation when you are on Anavar.
An initial 4-6 week cycle with a dosage of mg per day could possibly
be a wonderful start for beginners. You simply need to
fill out a kind, submit it, and wait in your order to be processed.
MAXLabs.co is dedicated to offering safe merchandise that don’t have harmful unwanted facet effects.
Pharmaceutical-grade Anavar was synthesized by scientists in an authorized laboratory when it
was authorized for medical causes. This was prescribed to patients suffering from cachexia, where muscle loss was occurring at an alarming rate,
rising the danger of mortality. Anavar’s half-life can increase past this range, relying on the age of the person. For occasion, its half-life could be as excessive as 13.three hours in the elderly (23).
Thus, if we state the half-life as 10.four hours,
a post-cycle remedy protocol should start fifty seven hours after the final dose.
Females will often use Anavar to achieve lean mass, as girls will be far more aware of the anabolic results of this steroid.
Lean muscle features will range considerably among ladies,
but over a 6-week cycle, some females can see excellent gains of
up to 5-10lbs, even while dropping some physique fat.
100mg of testosterone enanthate weekly for 12 weeks is sufficient to support the traditional perform of the hormone.
By limiting testosterone on this cycle, Anavar is left to take on the primary anabolic role, bringing about lean positive aspects
and incredible fats loss and firming throughout the cycle.
The hardness and dryness of Anavar positive aspects and fats
loss are among its strongest and most desirable benefits.
Not having to deal with water retention is a aid for anyone wanting to realize a shredded,
exhausting, and vascular physique.
References:
steroid use in women (https://lgmtech.co.uk/Employer/anavar-for-sale-online)
Chara –
Los andrógenos se descubrieron en la década de 1930 y se caracterizaron por
tener efectos descritos como androgénicos (es decir, virilizantes)
y anabólicos (p. ej., miotróficos, renotróficos).
El término esteroide anabólico se remonta al menos a mediados de la década de 1940, cuando se usó para describir
el concepto hipotético en ese momento de un esteroide derivado de la
testosterona con efectos anabólicos pero con efectos androgénicos mínimos
o nulos. Este concepto se formuló en base a la observación de que
los esteroides tenían proporciones de potencia
renotrófica a androgénica que diferían significativamente,
lo que sugería que los efectos anabólicos y androgénicos podrían ser disociables.
Por el contrario, los AAS reducidos en four,5α y algunos otros AAS (p.
ej., derivados de 19-nortestosterona 11β-metilados) no tienen riesgo de ginecomastia.
Además de la ginecomastia, los AAS con alta estrogenicidad tienen una mayor actividad
antigonadotrópica, lo que da como resultado una mayor potencia en la supresión del eje hipotálamo-pituitario-gonadal y
la producción de testosterona gonadal. Los efectos secundarios específicos
de la mujer incluyen aumento del vello corporal,
profundización permanente de la voz, agrandamiento del clítoris y disminución temporal
de los ciclos menstruales.
Esta planta, cuya droga se compone de hojas y raíces, también es muy utilizada
en la medicina ayurvédica para el rejuvenecimiento, la revitalización y la longevidad.
En un estudio de 2018 de Ziegenfuss, a una muestra de hombres
sanos se les administró una dosis de 500 miligramos (mg) de Ashwagandha por
día durante 12 semanas, todo junto con un entrenamiento progresivo
con sobrecargas durante four días a la semana. El resultado
obtenido mostró que las personas que habían tomado Ashwagandha también experimentaron mayores mejoras en la fuerza de
la parte inferior y superior del cuerpo, así como una distribución favorable de la masa corporal en comparación con las del grupo placebo.
Pero en esa misma época se descubrió que al administrar esteroides
anabólicos a los animales del laboratorio, esto aumentaba su masa muscular, lo que llevó a aplicarlos en el
terreno deportivo, primero a los culturistas y luego a atletas de otros deportes, llegando a alterar los
resultados de competiciones. Cuando se desarrollaron en los años
30 fue para utilizarlos en tratamientos médicos relacionados con problemas sexuales masculinos como
el hipogonadismo, un trastorno en el que los testículos no producen suficiente testosterona.
Aun hoy se emplean en tratamientos para retrasos de la pubertad, algunos tipos de
impotencia y el desgaste corporal de algunas enfermedades como
el sida.
Los investigadores concluyen que la vitamina D puede contribuir indirectamente a la salud
muscular al actuar sobre el tejido adiposo.
Actualmente, los científicos necesitan realizar más estudios para ver si esta conexión es aplicable a una muestra más grande de la población. El uso de estosagentes
se enfoca b�sicamente a la reducci�n de la fatiga durante los eventoscompetitivos y en las sesiones
de entrenamiento.
Los esteroides anabólicos incluyen la testosterona y
todos los fármacos química y farmacológicamente relacionados con la testosterona que
favorecen el crecimiento muscular; se dispone de numerosos
fármacos. Los esteroides anabólicos se utilizan clínicamente para tratar los niveles bajos de testosterona en el hipogonadismo masculino.
Además, dado que los esteroides anabólicos son anticatabólicos y mejoran la utilización de las proteínas, a veces se administran a pacientes que sufren quemaduras,
postrados o debilitados para prevenir la emaciación muscular.
Los esteroides anabólicos, técnicamente conocidos
como esteroides anabólicos androgénicos, son esteroides derivados del
grupo andrógeno en los que se trata de disminuir químicamente los efectos androgénicos y virilizantes e incrementar las acciones anabólicas.
Aunque se han logrado algunos avances, estas dos acciones fundamentales no han sido separadas completamente, y por eso los andrógenos anabólicos conservan sus efectos
virilizantes, más evidentes en la mujer y con el uso prolongado.
Últimamente han surgido nuevos tipos de esteroides anabólicos de diseño (DS),
muy populares por su bajo precio y la facilidad de acceso en el mercado negro.
Su consumo se relaciona con daños a nivel genético que podrían aumentar el riesgo de algunos
tipos de cáncer y alteraciones cromosómicas.
Sin embargo seria ridículo estar completamente en desacuerdo con estas observaciones debido
a que se han realizado sobre sujetos altamente entrenados y en atletas motivados.
Para mayor información sobre anabólicos esteroides, revisar
artículos sobre farmacología del deporte y medicina deportiva de los países que conformaron la ex
Unión Soviética. Los anabólicos esteroides
pueden bloquear los efectos de hormonas como el
cortisol que producen ruptura del tejido, durante
y después del ejercicio, con la posibilidad de prevenir la ruptura de tejido
después del trabajo intenso. El cortisol y hormonas
relacionadas, secretadas por la corteza adrenal, también poseen receptores dentro de las
células musculares. El cortisol produce ruptura de proteínas y es secretado durante el ejercicio para incrementar la utilización de proteínas como flamable y para suprimir la inflamación que acompaña el
daño tisular. Muchos atletas han planteado que los anabólicos esteroides los ayudan a entrenar con mayor intensidad y recuperarse con mayor velocidad.
Las lipoproteínas de baja densidad (LDL o colesterol malo) aumentan sus niveles, y las lipoproteínas de alta densidad (HDL
o colesterol bueno) disminuyen. Se ha informado de complicaciones cardiovasculares
graves, como hipertensión arterial, accidente cerebrovascular, infarto de miocardio y coágulos de sangre,
relacionadas con el consumo de esteroides anabolizantes.
Esto se debe al hecho de que mientras se usan esteroides anabólicos,
la producción pure de esta hormona disminuye temporalmente – el cuerpo detecta
que tiene una cantidad suficiente de andrógenos, por lo que detiene su producción. Sin su presencia en el cuerpo, un gran número de procesos esenciales dejan de tener
lugar. Además, es una hormona con altas capacidades
anabólicas, lo que garantiza un excelente crecimiento.
Si poco claro es el papel precise de los anabolizantes como recursos
terapéuticos, su abuso como fármaco es, como mínimo, preocupante.
Los hombres que abusan de los esteroides corren el riesgo de
desarrollar la próstata y los senos, y las mujeres pueden crecer el vello corporal y experimentar una voz más
grave. Tanto hombres como mujeres pueden experimentar problemas graves de acné y ansiedad.
En casos graves, los esteroides anabólicos pueden representar una amenaza de ataque cardíaco o cáncer.
El uso a largo plazo puede provocar que el cuerpo produzca demasiados glóbulos rojos (eritrocitos) y niveles anómalos de grasas (lípidos) en la sangre.
La mayoría de las páginas y foros específicos sobre
el tema recomiendan pautas, dosis, combinaciones, formas de
uso o manejo de efectos secundarios que no están basados en estudios científicos y pueden predisponer a problemas
de salud. La Agencia Mundial Antidopaje (AMA) mantiene la lista de sustancias para mejorar el rendimiento
utilizadas por muchos organismos deportivos importantes e incluye todos los agentes anabólicos, lo
que incluye todos los AAS y precursores, así como todas las hormonas y sustancias relacionadas.
España ha aprobado una ley antidopaje que crea una agencia nacional antidopaje.
Italia aprobó una ley en 2000 donde las penas van hasta tres años de prisión si
un atleta ha dado positivo por sustancias prohibidas.En 2006,
el presidente ruso, Vladimir Putin, promulgó
la ratificación de la Convención Internacional
contra el Dopaje en el Deporte, que fomentaría la cooperación con la AMA.
Muchos otros países tienen una legislación comparable que prohíbe AAS en los deportes, incluidos Dinamarca, Francia, los Países Bajos y
Suecia. Los cambios en los niveles de testosterona endógena también pueden contribuir a las diferencias en la relación miotrófica-androgénica entre la testosterona y los AAS sintéticos.
Los agonistas de AR son antigonadotrópicos, es decir, suprimen la producción de testosterona gonadal de
manera dependiente de la dosis y, por lo tanto, reducen las concentraciones sistémicas de testosterona.
Por supuesto, en ambos casos, tanto la longitud de la aguja como su
diámetro (cuanto mayor sea el número G, menor será el
diámetro de la aguja) pueden ser ligeramente mayores o
menores. En el caso del método subq, el tamaño óptimo de
la aguja es de 30G x 0.8cm (0.3″). En vistas del trabajo realizado,
pensamos que el campo de los anabolizantes
esteroideos es muy amplio dentro de la relación que tiene con la Fisiología del Ejercicio.
De ahí, se creará una copia, el ARNm, que saldrá del núcleo de la fibra muscular
al sarcoplasma donde será captada por el retículo endoplasmático rugoso.
Los más comunes son los ésteres de testosterona y derivados de la misma (Tabla 1)
(2).
A veces, los AAS ilegales se venden en gimnasios y competencias, y por correo, pero también se pueden obtener a través de farmacéuticos,
veterinarios y médicos. Además, un número
significativo de productos falsificados se venden como AAS, en specific a
través de pedidos por correo desde sitios net que se hacen pasar por farmacias en el extranjero.
UU., la importación en el mercado negro continúa desde
México, Tailandia y otros países donde los esteroides están más fácilmente disponibles, ya que son legales.
Algunos AAS que son o pueden ser reducidos en 5α, incluyendo testosterona,
DHT, estanozolol y metiltestosterona, entre muchos otros, pueden o pueden modular
el receptor GABA A, y esto puede contribuir como un mecanismo alternativo o adicional a sus efectos en el sistema nervioso central.
Un estudio en animales encontró que dos tipos diferentes de elementos de respuesta
a los andrógenos podrían responder de manera diferente a la
testosterona y la DHT tras la activación del AR.
References:
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